Thermo Fisher Scientific RFXANK Monoclonal Antibody (OTI2B6)
RFXANK 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간 반응성, 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적. 면역학 및 MHC class II 관련 연구용에 적합.
- 카탈로그번호
- MA525864
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RFXANK Monoclonal Antibody (OTI2B6)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Full length human recombinant protein of RFXANK produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725219 |
Target Information
Major histocompatibility (MHC) class II molecules are transmembrane proteins that play a central role in immune system development and regulation.
The RFXANK protein, together with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates transcription.
This complex associates with the MHC class II transactivator, controlling cell type specificity and inducibility of MHC class II gene expression.
RFXANK contains ankyrin repeats involved in protein-protein interactions.
Mutations in this gene are linked to bare lymphocyte syndrome type II, complementation group B.
Two transcript variants encoding different isoforms have been described, with only one showing activation activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.