Thermo Fisher Scientific CD300e Polyclonal Antibody
인간 CD300e 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. CD300e의 면역세포 활성화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CD300e. Recombinant protein control fragment (Product # RP-90569) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639542 |
Product Specific Information
Immunogen sequence:
TVWCQYESMY KGYNKYWCRG QYDTSCESIV ETKGEEKVER NGRVSIRDHP EALAFTVTMQ NLNEDDAGSY WCKIQTVWVL DSWSRDPSDL VRVYVSPAIT TPRRTTHPAT PPIFLVVNPG RNLSTGEVLT QNSGFR
- Highest antigen sequence identity to orthologs:
- Mouse: 55%
- Rat: 56%
Target Information
CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. It interacts with TYRO protein tyrosine kinase-binding protein and functions as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes and is downregulated on immature dendritic cells. It also interacts with DAP-12, mediating activating signals. Activation of CD300e enhances the alloreactive response of naïve T cells.
Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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