Thermo Fisher Scientific LRP15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LRP15. Recombinant protein control fragment (Product #RP-90526). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRP15,uniProtId:Q96PB8-1,ncbiNodeId:9606,antigenRange:34-178,antigenLength:259,antigenImageFileName:PA5-53323_LRP15_Q96PB8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53323_LRP15_Q96PB8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643478

Product Specific Information

Immunogen sequence: CPKGCLCSSS GGLNVTCSNA NLKEIPRDLP PETVLLYLDS NQITSIPNEI FKDLHQLRVL NLSKNGIEFI DEHAFKGVAE TLQTLDLSDN RIQSVHKNAF NNLKARARIA NNPWHCDCTL QQVLRSMASN HETAHNVICK TSVLD

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.