Thermo Fisher Scientific Unc18-2 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Unc18-2 protein. Validated for WB, IHC, and ICC applications. High specificity with recombinant protein immunogen. Supplied as liquid, unconjugated form with 0.1 mg/mL concentration. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Unc18-2. Recombinant protein control fragment (Product #RP-90659). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649268 |
Product Specific Information
Immunogen sequence:
CPEPLFSELG RSRLAKVVKT LKEIHLAFLP YEAQVFSLDA PHSTYNLYCP FRAEERTRQL EVLAQQIATL CATLQEYPAI RYRKGPEDTA QLAHAVLAKL N
Antigen sequence identity:
- Mouse: 94%
- Rat: 96%
Target Information
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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