Thermo Fisher Scientific mGluR1 alpha Polyclonal Antibody
Rabbit polyclonal antibody targeting mGluR1 alpha for WB, IHC, and ICC applications. High specificity and sensitivity with 1 mg/mL concentration. Suitable for neuroscience research on glutamate receptor signaling. For research use only.
- 카탈로그번호
- RA19065-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific mGluR1 alpha Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:250 |
| Immunocytochemistry (ICC/IF) | 1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 1159-1171 SSVPSSPVSESVL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It was long thought to act only on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors, which mediate fast excitatory synaptic transmission.
Recent findings show that glutamate also regulates enzymes producing second messengers via specific G-protein-coupled receptors, known as metabotropic glutamate receptors (mGluRs).
Group-I mGluRs (including mGluR1a and mGluR5) stimulate phospholipase C, leading to increased phosphoinositide turnover and calcium release from internal stores.
Group-II and Group-III receptors (including mGluR2 and mGluR3) are coupled to inhibition of adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.