Thermo Fisher Scientific Alpha 2c Adrenergic Receptor Polyclonal Antibody
Alpha 2C 아드레날린 수용체를 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 적합하며, 고순도 액상 형태로 제공. 신경전달 조절 연구에 활용 가능. 연구용으로만 사용.
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- RA19064-xxxxx (2개 옵션)
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Thermo Fisher Scientific Alpha 2C Adrenergic Receptor Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 309–324 GAEGGAGGADGQGAGP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily, including three highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors play a critical role in regulating neurotransmitter release from sympathetic nerves and adrenergic neurons in the central nervous system.
Mouse studies show both alpha2A and alpha2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and central noradrenergic neurons. The alpha2A subtype inhibits transmitter release at high stimulation frequencies, while the alpha2C subtype modulates neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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