Thermo Fisher Scientific Noggin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Noggin protein. Suitable for Western blot applications at 1:1,000–1:2,000 dilution. Supplied as a liquid, unconjugated form at 1 mg/mL concentration. Involved in studies of developmental processes and BMP sign...
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- RA19066-100UL
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide comprising residues 156–170 [PVLYAWNDLGSRFWP] of the human Noggin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Noggin is involved in numerous developmental processes such as neural tube fusion and joint formation. Organ morphogenesis is initiated by downgrowth from epithelial stem cells, regulated by signals from WNT3A (stabilizing beta-catenin) and Noggin (a BMP inhibitor). Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by joint fusion defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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