Thermo Fisher Scientific CDKN2B (Isoform 2) Polyclonal Antibody
CDKN2B Isoform 2에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응하며 Western blot에 적합합니다. 액상형으로 안정적인 보존이 가능하며, 암 연구 및 세포주기 조절 관련 연구에 활용됩니다.
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Thermo Fisher Scientific CDKN2B (Isoform 2) Polyclonal Antibody
Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RQGARERGARP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933475 |
Product Specific Information
- This antibody is expected to recognize isoform 2 (NP_511042.1) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The CDKN2B gene lies adjacent to the tumor suppressor gene CDKN2A, in a region frequently mutated and deleted in various tumors. It encodes a cyclin-dependent kinase inhibitor that forms complexes with CDK4 or CDK6, preventing kinase activation and regulating cell cycle G1 progression. Expression of this gene is induced by TGF beta, suggesting its role in TGF beta–mediated growth inhibition. Two alternatively spliced transcript variants encoding distinct proteins have been reported.
[provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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