Thermo Fisher Scientific Haptoglobin alpha Polyclonal Antibody
Thermo Fisher Scientific의 Haptoglobin alpha Polyclonal Antibody는 인간 시료에 반응하는 염소 유래 IgG 항체로, Western blot에 적합합니다. QCKNYYKLRTEGD(aa 51-63) 펩타이드로 면역화되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–0.03 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence QCKNYYKLRTEGD (aa 51–63) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933469 |
Product Specific Information
- Recognizes both reported isoforms (NP_005134.1; NP_001119574.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
Haptoglobin captures free plasma hemoglobin to enable hepatic recycling of heme iron and prevent kidney damage. It also acts as an antioxidant, has antibacterial activity, and modulates the acute phase response. Hemoglobin/haptoglobin complexes are cleared by macrophage CD163 receptors through lysosomal degradation pathways.
The uncleaved form of allele alpha-2 (2-2), known as zonulin, plays a role in intestinal permeability, regulating tight junction disassembly and immune tolerance.
[PMID: 21248165]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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