Thermo Fisher Scientific DDX3 Polyclonal Antibody
DDX3 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, RNA 헬리케이스 연구 및 암 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the center of human DDX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154390 |
Product Specific Information
- Suggested positive control: HepG2 cell lysate
- PA5-20225 can be used with blocking peptide PEP-0338
Target Information
The protein encoded by this gene belongs to the large DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif, and exhibits ATP-dependent RNA helicase activity.
It has both RNA- and DNA-stimulated ATPase activity and functions in the nucleus and cytoplasm.
Nuclear roles include:
- Transcriptional regulation
- mRNP assembly
- Pre-mRNA splicing
- mRNA export
Cytoplasmic roles include:
- Translation
- Cellular signaling
- Viral replication
Misregulation of this gene is implicated in tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes are found on chromosome 4 and the X chromosome. Alternative splicing produces multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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