Thermo Fisher Scientific PAK2 Polyclonal Antibody
PAK2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 세포골격 조절, 세포 이동, 세포주기 및 세포사멸 연구에 활용됩니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of human p21 (CDKN1A)-activated kinase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase involved in multiple signaling pathways, including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation. It functions as a downstream effector of the small GTPases CDC42 and RAC1. Activation occurs through binding with active CDC42 and RAC1, leading to conformational change and autophosphorylation on several serine and/or threonine residues. Full-length PAK2 promotes cell survival and growth. PAK proteins are key mediators linking Rho GTPases to cytoskeletal reorganization and nuclear signaling and are implicated in diverse biological processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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