Thermo Fisher Scientific Phospho-CD104 (Tyr1510) Polyclonal Antibody
Phospho-CD104 (Tyr1510) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. WB, IHC, ELISA에 적합하며 고순도 항원 친화 크로마토그래피로 정제됨. PBS 기반 저장 버퍼와 안정적 보관 조건 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Integrin beta4 around the phosphorylation site of Y1510 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609375 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Integrins are heterodimers composed of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different alpha-beta combinations determine ligand-binding specificity. Integrins mediate cell-matrix and cell-cell adhesion and transduce signals regulating gene expression and cell growth. The integrin beta 4 subunit acts as a receptor for laminins, commonly associating with the alpha 6 subunit, and plays a critical role in invasive carcinoma biology. Mutations in this gene are linked to epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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