Thermo Fisher Scientific EHD1 Polyclonal Antibody
EHD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EHD1 (Accession Q9H4M9), corresponding to amino acid residues F422–V472 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852330 |
Product Specific Information
Antibody detects endogenous levels of total EHD1.
Target Information
EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.
It also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulating neurite outgrowth.
EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The EH domain is an important motif in proteins involved in protein-protein interactions and intracellular sorting.
EHD1 is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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