Thermo Fisher Scientific WASP Polyclonal Antibody
WASP 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 0.5–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC-F) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human WASP (129–156aa: ADEDEAQAFRALVQEKIQKRNQRQSGDR) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747338 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The Wiskott-Aldrich syndrome family of proteins share similar domain structures and are involved in transducing signals from cell surface receptors to the actin cytoskeleton. These proteins interact with multiple signaling molecules, including the small GTPase Cdc42 and the cytoskeletal organizing complex Arp2/3.
Wiskott-Aldrich syndrome is a rare, X-linked recessive disease characterized by immune dysregulation and microthrombocytopenia, caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein expressed exclusively in hematopoietic cells, exhibiting signaling and cytoskeletal abnormalities in affected patients. A transcript variant with an alternative promoter and different 5′ UTR sequence has been described, though its full-length nature remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-80224_WASP_P42768-1_Rabbit.svg, PA5-80224_WASP_P42768-1_Rabbit_PDP.jpeg)
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