Thermo Fisher Scientific HPS1 Monoclonal Antibody (5G12G2)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1:10,000

Product Specifications

Product Specific Information

MA5-15381 targets HPS1 in indirect ELISA and WB applications, showing reactivity with Human samples.
The MA5-15381 immunogen is a purified recombinant fragment of HPS1 expressed in E. coli.

Target Information

Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous, autosomal recessive disorder characterized by oculocutaneous albinism, lysosomal storage defects, and prolonged bleeding due to platelet storage pool deficiency.
There are 10 HPS genes encoding HPS proteins that interact within three distinct ubiquitously expressed protein complexes (biogenesis of lysosome-related organelle complexes). Defects in these genes cause HPS.
HSP-1 is a component of multiple cytoplasmic organelles and is important for their normal development and function. It plays a role in intracellular protein sorting.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.