Thermo Fisher Scientific PBX1 Monoclonal Antibody (OTI1H5), TrueMAB
PBX1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1H5). Western blot 및 ICC/IF에 적합하며, Human 시료에 반응. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H5 |
| Immunogen | Full length human recombinant protein of human PBX1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PBX1 gene encodes a nuclear protein belonging to the PBX homeobox family of transcription factors. It plays a role in osteogenesis regulation and skeletal patterning.
A chromosomal translocation t(1;19) involving PBX1 and TCF3/E2A is associated with pre-B-cell acute lymphoblastic leukemia, producing a fusion protein that constitutively activates PBX-regulated genes.
Alternative splicing results in multiple isoforms of PBX1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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