Thermo Fisher Scientific ORM2 Polyclonal Antibody
Thermo Fisher Scientific의 ORM2 Polyclonal Antibody는 마우스 ORM2 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/50% 글리세롤에 보관하며 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Orosomucoid 2 protein (amino acids 19–207 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903820 |
Target Information
AGP (α1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It regulates interactions between blood and endothelial cells and mediates cell extravasation during infection and inflammation, along with haptoglobin and C-reactive protein. Expression is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides.
AGP binds basic drugs with high affinity and low capacity at physiological pH. In human plasma, AGP levels range from 0.5–1.4 mg/mL and increase during acute inflammation, making it a useful marker for inflammatory conditions. Multiple AGP genes exist (AGP-1, AGP-2, AGP-3, AGP-8). AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of AGP-1 is linked to sarcoidosis and other immunogenetic diseases, while AGP-2 mutations are associated with various carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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