Thermo Fisher Scientific NeuroD1 Monoclonal Antibody (4G12B4)
NeuroD1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, Flow cytometry에 적합합니다. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도. 인간 시료 반응성. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G12B4 |
| Immunogen | Purified recombinant fragment of human NeuroD (aa 26–91) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at −20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898493 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
NeuroD1 is a transcriptional activator functioning as a differentiation factor during neurogenesis. It binds to the insulin gene E-box and requires dimerization with another basic helix-loop-helix (bHLH) protein for efficient DNA binding. Defects in NEUROD1 are associated with maturity onset diabetes of the young type VI (MODY6), a non-insulin-dependent diabetes mellitus with autosomal dominant inheritance, onset in young adulthood, and a primary defect in insulin secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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