Thermo Fisher Scientific Alpha Sarcoglycan Polyclonal Antibody
Alpha Sarcoglycan 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, IP 등에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 제품. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 209–254 of human Sarcoglycan-alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553881 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 50 kDa.
Purity is >95% by SDS-PAGE.
Target Information
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans form a complex localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four subunit proteins—alpha-, beta-, gamma-, and delta-sarcoglycan—constitute the complex on the muscle cell surface.
Genetic defects in any of these proteins lead to loss or reduction of the sarcoglycan complex, associated with autosomal recessive muscular dystrophy (sarcoglycanopathy).
In smooth muscle, beta- and delta-sarcoglycans associate with epsilon-sarcoglycan, homologous to alpha-sarcoglycan. A deficiency in delta-sarcoglycan causes the Syrian hamster BIO.14 cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-37050_Alpha_Sarcoglycan_Q16586-1_Rabbit.svg, PA5-37050_Alpha_Sarcoglycan_Q16586-1_Rabbit_PDP.jpeg)
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