Thermo Fisher Scientific LSM11 Monoclonal Antibody (OTI2G7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

LSm11 is a 360 amino acid nuclear protein belonging to the LSm subfamily of snRNP Sm proteins.
It contains an N-terminal domain required for pre-mRNA cleavage and binds specifically to U7 snRNA, playing roles in cell cycle regulation and cell growth.
The LSm11 gene maps to human chromosome 5, which spans 181 million base pairs (~6% of the human genome).
Deletions in chromosome 5 are associated with Cri du chat syndrome and certain leukemias and myelodysplastic syndromes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.