Thermo Fisher Scientific GHRHR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

-

Immunocytochemistry (ICC/IF)

1:3,000

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide, KLH conjugated, corresponding to residues R(403) T R A K W T T P S R S A A K V L T S M(422) of human GHRH-R. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GHRHR,uniProtId:Q02643-1,ncbiNodeId:9606,antigenRange:403-422,antigenLength:423,antigenImageFileName:PA3-117_GHRHR_Q02643-1_Rabbit.svg,antigenImageFileNamePDP:PA3-117_GHRHR_Q02643-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2111434

Product Specific Information

PA3-117 detects GHRH-R in human samples.

PA3-117 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40 kDa protein representing GHRH-R in human samples. In immunohistochemistry, GHRH-R immunoreactivity is predominantly localized at the plasma membrane.

The PA3-117 immunizing peptide corresponds to amino acid residues 403-422 from human GHRH-R.

Target Information

Growth Hormone Releasing Hormone (GHRH) is a member of a family of peptide hormones that also includes VIP (vasoactive intestinal polypeptide) and PACAP (pituitary adenylate cyclase-activating polypeptide). It is a hypothalamic peptide that binds to G-protein coupled receptors to stimulate secretion and synthesis of growth hormone (GH). GHRH receptor proteins have been identified on the plasma membrane of primary human tumor cells, and are thought to be involved in the growth of a variety of cancer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.