Thermo Fisher Scientific Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody
Phospho-JNK1/JNK2 (Thr183, Tyr185) 폴리클로날 항체로 Western blot, IHC, ICC에 적합. 인간, 생쥐, 랫트 시료에서 인산화된 JNK/SAPK 검출. 친화 크로마토그래피로 정제된 0.5 mg/mL 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:4,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated peptide (pT183-P-pY185) based on human JNK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2235043 |
Product Specific Information
PA1-9593 detects Phospho-JNK/SAPK in human, mouse, and rat samples.
It has been successfully used in Western blot, immunohistochemistry, and immunocytochemistry procedures.
By Western blot, PA1-9593 detects 46 kDa and 54 kDa proteins representing Phospho-JNK/SAPK.
The immunogen is a phosphorylated peptide (pT183-P-pY185) based on human JNK.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases.
MAPKs are serine-threonine protein kinases activated by various extracellular stimuli, mediating signal transduction from the cell surface to the nucleus.
JNK plays roles in proliferation, differentiation, transcription regulation, and development.
JNK pathways are activated by stress and inflammatory signals.
JNK is expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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