Thermo Fisher Scientific Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:4,000

-

Immunohistochemistry (IHC)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Phosphorylated peptide (pT183-P-pY185) based on human JNK if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JNK1/JNK2,uniProtId:P45983-1,ncbiNodeId:9606,antigenRange:183|185,antigenLength:427,antigenImageFileName:PA1-9593_JNK1JNK2_P45983-1_Rabbit.svg,antigenImageFileNamePDP:PA1-9593_JNK1JNK2_P45983-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:JNK1/JNK2,uniProtId:P45984-1,ncbiNodeId:9606,antigenRange:183|185,antigenLength:424,antigenImageFileName:PA1-9593_JNK1JNK2_P45984-1_Rabbit.svg,antigenImageFileNamePDP:PA1-9593_JNK1JNK2_P45984-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2235043

Product Specific Information

PA1-9593 detects Phospho-JNK/SAPK in human, mouse, and rat samples.

PA1-9593 has been successfully used in Western blot, immunohistochemistry, and immunocytochemistry procedures. By Western blot, PA1-9593 detects a 46 kDa and 54 kDa protein representing Phospho-JNK/SAPK.

PA1-9593 immunogen is a phosphorylated peptide (pT183-P-pY185) based on human JNK.

Target Information

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.