Thermo Fisher Scientific Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody
Phospho-JNK1/JNK2 (Thr183, Tyr185) 인산화 단백질을 인식하는 다클론 항체로, Western blot, IHC, ICC, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:500–1:2,000 | - |
| ELISA | 1:1,000–1:4,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated peptide (pT183-P-pY185) based on human JNK/SAPK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2140859 |
Product Specific Information
- PA1-9594 detects Phospho-JNK/SAPK in human, mouse, and rat samples.
- Successfully used in Western blot, immunohistochemistry, ELISA, and immunocytochemistry applications.
- Detects 46 kDa and 54 kDa proteins representing Phospho-JNK/SAPK in Western blot.
- Immunogen: phosphorylated peptide (pT183-P-pY185) based on human JNK/SAPK.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are serine-threonine protein kinases activated by various extracellular stimuli, mediating signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
JNK pathways are activated by stress and inflammatory signals and expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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