Thermo Fisher Scientific MYOD Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MYOD1.

Target Information

The Myogenic determination gene (MyoD) was first identified by its ability to convert embryonic mouse fibroblast cells into muscle cells. Forced expression of the MyoD (human homolog is myf3) gene in various normal and neoplastic cells can either convert the cells to muscle cells or activate otherwise inactive muscle-specific genes.
The regulatory domain of the MyoD gene product lies within a 70 amino acid region comprising a basic DNA-binding motif and a helix-loop-helix (HLH) dimerization motif.
Subsequent studies identified three other genes sharing sequence homology with the basic HLH domain of MyoD: myf5, myogenin (human homolog is myf4), and myf6 (also known as MRF4 and herculin).

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.