Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI3F4), TrueMAB
PDGFRA 단백질을 인식하는 Mouse IgG2b 형 단일클론 항체로, Western blot에 적합합니다. 인간 PDGFRA(aa 789–1089) 재조합 단백질을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 789–1089 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds platelet-derived growth factors, which act as mitogens for mesenchymal cells. The receptor’s ligand determines whether it forms a homodimer or heterodimer with PDGFRB. Knockout mouse studies show PDGFRA’s crucial role in kidney development, as heterozygous mice display defective renal phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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