Thermo Fisher Scientific DRD3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DRD3. Validated for IHC (paraffin) with high species cross-reactivity. Purified via antigen affinity chromatography, supplied in PBS with 0.1% sodium azide. Ideal for neuroscience and receptor signaling research.
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- PA533482
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 16–32 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Dog, Horse, Hamster, Human, Mouse, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human DRD3 (Dopamine Receptor D3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550862 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Mouse, Dog, Bat, Hamster, Panda, Horse, Pig (100%).
Target Information
The DRD3 gene encodes the D3 subtype of the five dopamine receptors (D1–D5). Its activity is mediated by G proteins that inhibit adenylyl cyclase. The receptor is localized in limbic brain regions related to cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing may produce multiple transcript variants, some subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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