Thermo Fisher Scientific DRD2 Polyclonal Antibody
Rabbit polyclonal antibody against human DRD2 for IHC(P) applications. Recognizes dopamine receptor D2 involved in neuromodulation and reward behavior. High specificity and purity via antigen affinity chromatography. Suitable for neuroscience and recep...
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Applications
- Immunohistochemistry (Paraffin) [IHC(P)]: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human DRD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550860 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Marmoset (100%); Gibbon, Monkey, Rabbit (95%); Dog, Bovine, Panda, Horse, Pig (89%).
Target Information
The DRD2 Dopamine Receptor is involved in neuromodulation of appetitive behaviors and may be linked to alcoholism and other substance-use disorders.
Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified.
DRD2 is expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord.
ESTs have been isolated from normal pituitary and from brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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