
Thermo Fisher Scientific DUSP22 Polyclonal Antibody
DUSP22 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 2–22 µg/mL 농도로 사용 가능. 인간, 소, 말, 토끼 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS와 0.1% sodium azide 함유. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–22 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Human, Non-human primate, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from near N-terminus of human DUSP22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550867 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Horse, Rabbit (100%);
Mouse, Rat (94%); Elephant, Chicken (88%); Xenopus (82%).
Target Information
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways activated by various stimuli. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, selective for dephosphorylating phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by growth factors and cellular stresses, thereby negatively regulating MAP kinase members including MAPK/ERK, SAPK/JNK, and p38.
DUSP22 dephosphorylates ERK2 MAP kinase and JNK. It is highly expressed in the thymus and detectable in monocytes and lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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