Thermo Fisher Scientific DRD2 Polyclonal Antibody
Rabbit Polyclonal DRD2 항체로, 인간 및 다양한 종에 반응합니다. 면역조직화학(IHC-P)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 도파민 수용체 DRD2 연구용으로 적합하며, 신경조절 및 행동 연구에 활용됩니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC-P): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Human, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human DRD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550861 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Ferret, Bat, Bovine, Dog, Elephant, Panda, Horse, Rabbit (100%)
Gibbon, Monkey, Pig (94%)
Target Information
The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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