Thermo Fisher Scientific PPP2R1B Polyclonal Antibody
PPP2R1B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P/F) 및 ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. KLH 결합 합성 펩타이드로 면역화. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PPP2R1B, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis, and apoptosis. Protein phosphatases are key regulators in this process. The protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified: PP1, PP2A, PP2B (calcineurin), and PP2C. An additional catalytic subunit, PPX (also known as PP4), is part of a novel PP family. The PP2A family includes PP2A alpha and PP2A beta subunits, which associate with various regulatory subunits such as PP2A-A alpha/beta, PP2A-B alpha/beta, PP2A-C alpha/beta, and PP2A-B56 alpha/beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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