Thermo Fisher Scientific ROR-gamma/RORC (RAR-related Orphan Receptor C) Monoclonal Antibody (RORC/2942)
인간 ROR-gamma/RORC 단백질을 인식하는 mouse monoclonal 항체로, ELISA와 peptide array에 사용 가능. Protein A/G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공. PBS(pH 7.4) buffer에 보존제가 포함되지 않으며, -20°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 6097-MSM2-P1ABX
- 판매단위
- pk
카탈로그
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Applications
ELISA (ELISA)
- Assay-dependent
Peptide Array (Array)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RORC/2942 |
| Immunogen | Recombinant full-length human RORC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It acts as a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and plays a regulatory role in apoptosis during thymopoiesis.
ROR gamma inhibits Fas ligand and IL2 expression and directs differentiation of proinflammatory IL-17+ T helper cells. It shares 50–51% sequence identity with RORA and RORB, and 88% identity with mouse ROR gamma. Expression is high in skeletal muscle and lower in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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