Thermo Fisher Scientific ROR-gamma/RORC (RAR-related Orphan Receptor C) Monoclonal Antibody (RORC/2941)
RORC/2941 단클론 항체로 인간 ROR-gamma 단백질을 특이적으로 인식. IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능. 단백질 A/G 정제, 액상 형태, 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RORC/2941 |
| Immunogen | Recombinant full-length human RORC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It functions as a ligand-activated transcription factor and plays an essential role in lymphoid organogenesis, including lymph nodes and Peyer’s patches. ROR gamma regulates apoptosis during thymopoiesis, inhibits Fas ligand and IL2 expression, and directs differentiation of proinflammatory IL-17⁺ T helper cells. It shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. High expression is observed in skeletal muscle, with lower levels in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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