
Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI9B7), TrueMAB
인간 CD4 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 면역세포 및 HIV 연구에 적합한 고품질 TrueMAB 항체.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9B7 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human CD4 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The CD4 antigen is involved in recognition of MHC class II molecules and acts as a co-receptor for HIV. It is primarily expressed in T helper cells, but also found in monocytes, macrophages, dendritic cells, and various lymphoid tissues such as thymus, lymph nodes, tonsils, and spleen.
CD4 contributes to early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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