Thermo Fisher Scientific TWEAK Monoclonal Antibody (CARL-1), PE
인간 TWEAK(CD255) 단백질을 인식하는 단클론 항체로, PE 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 4°C 암조건에서 보관하며, 세포 표면 단백질 분석 및 세포사멸 연구에 활용 가능합니다.
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Applications
- Flow Cytometry (Flow): 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CARL-1 |
| Immunogen | Human CD255-transfected 2PK-3 cells |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745564 |
Additional Formats
- Unconjugated: MA5-28606
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD255 / TWEAK, a type II transmembrane protein of the TNF superfamily that can weakly induce apoptosis in many cell types.
Recommended dilution: 10 µL for 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF superfamily (TNFSF). It is a type II transmembrane protein, though a smaller, biologically active soluble form can be generated by cleavage near the membrane.
TWEAK exhibits multiple biological activities, including:
- Stimulation of cell growth and angiogenesis
- Induction of inflammatory cytokines
- Stimulation of apoptosis
TWEAK signals via the TweakR/Fn14 receptor, similar to other TNFSF members that bind receptors lacking death domains.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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