Thermo Fisher Scientific CXCL10 Recombinant Rabbit Monoclonal Antibody (10H11L3)
CXCL10 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능. 높은 특이성과 재현성을 제공하며, lot-to-lot 일관성이 우수함. 동물 유래 성분이 없는 포뮬레이션으로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | – |
| Immunohistochemistry (IHC) | – | 3 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:20 | – |
| Immunocytochemistry (ICC/IF) | 1:200 | – |
| Flow Cytometry (Flow) | – | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10H11L3 |
| Immunogen | Proprietary |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532429 |
Product Specific Information
Intact IgG appears on a non-reducing gel as a ~150 kDa band and, upon reduction, generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
IP-10 (Interferon-gamma induced protein 10 kD) — also known as cytokine responsive gene 2 (Crg-2) or mob-1 in mouse — belongs to the CXC chemokine superfamily and was first cloned in 1985. Although its biological functions are not fully understood, IP-10 is known to:
- Stimulate monocytes, NK, and T-cell migration
- Regulate T-cell and bone marrow progenitor maturation
- Modulate adhesion molecule expression
- Inhibit angiogenesis
IP-10 and Mig share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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