Thermo Fisher Scientific ApoC3 Recombinant Rabbit Monoclonal Antibody (6H21L11)

Applications

Western Blot (WB)

• Tested Dilution: 1–3 µg/mL
• View 1 publication

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1–3 µg/mL

Product Specifications

Product Specific Information

• Predicted to react with mouse, non-human primate, and rabbit based on sequence homology.
• Intact IgG appears on a non-reducing gel as ~150 kDa band; upon reduction generates ~25 kDa (light chain) and ~50 kDa (heavy chain) bands.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits and screen for optimal clones.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

Apolipoprotein C-III (apo-CIII) is encoded by the APOC3 gene and is a component of very low-density lipoprotein (VLDL). It inhibits lipoprotein lipase and hepatic lipase, delaying the catabolism of triglyceride-rich particles. The APOA1, APOC3, and APOA4 genes are closely linked in both rat and human genomes. Elevated apoC-III levels are associated with hypertriglyceridemia.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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