Thermo Fisher Scientific ORC6 Polyclonal Antibody
Thermo Fisher Scientific의 ORC6 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot, IHC, ELISA에 사용 가능합니다. 핵 내 ORC6 단백질 검출에 적합하며, 친화 크로마토그래피로 정제된 고품질 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–252 of human ORC6 (NP_055136.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914486 |
Product Specific Information
- Positive test controls: Jurkat, SW620, PC-3, HeLa, Mouse brain, Rat brain
- Subcellular localization: Nucleus
Immunogen sequence:
MGSELIGRLA PRLGLAEPDM LRKAEEYLRL SRVKCVGLSA RTTETSSAVM CLDLAASWMK CPLDRAYLIK LSGLNKETYQ SCLKSFECLL GLNSNIGIRD LAVQFSCIEA VNMASKILKS YESSLPQTQQ VDLDLSRPLF TSAALLSACK ILKLKVDKNK MVATSGVKKA IFDRLCKQLE KIGQQVDREP GDVATPPRKR KKIVVEAPAK EMEKVEEMPH KPQKDEDLTQ DYEEWKRKIL ENAASAQKAT AE
Target Information
The origin recognition complex (ORC) is a highly conserved six-subunit protein complex essential for the initiation of DNA replication in eukaryotic cells.
In yeast, ORC binds specifically to origins of replication and serves as a platform for the assembly of initiation factors such as Cdc6 and Mcm proteins.
The ORC6 protein is a subunit of this complex and plays a crucial role in coordinating chromosome replication and segregation with cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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