Thermo Fisher Scientific TNFRSF9 Monoclonal Antibody (5F8)
인간 TNFRSF9(CD137, 4-1BB)을 인식하는 Mouse IgG1 단클론 항체. Western blot 및 ELISA에 적합. PBS 용액 형태로 제공되며, 보존제 없이 -20°C에서 보관. 활성 T세포 표지 및 면역조절 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F8 |
| Immunogen | TNFRSF9 (AAH06196.1, 46 a.a. approximately 128 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:SPCPPNSFSS AGGQRTCDIC RQCKGVFRTR KECSSTSNAE CDCTPGFHCL GAGCSMCEQD CKQGQELTKK GCKDAAFGTF NDQ
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells.
Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
CD137 signaling maintains survival of activated and memory T cells, promotes clonal expansion, and modulates cytokine release influencing monocyte survival.
Soluble CD137 may act as a negative regulator in immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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