Thermo Fisher Scientific TNFRSF9 Monoclonal Antibody (4H4)
TNFRSF9(4-1BB/CD137) 단백질을 인식하는 Mouse IgM 단클론 항체. ELISA에 최적화되어 있으며, 액상 형태로 제공됨. 활성화된 T세포 표면의 CD137 발현 연구에 적합. -20°C 보관, 동결/해동 반복 피해야 함.
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Applications
- ELISA (ELISA): Tested at 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H4 |
| Immunogen | TNFRSF9 (AAH06196.1, 24 a.a. ~ 186 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Sequence of this protein is as follows:
LQDPCSNCPA GTFCDNNRNQ ICSPCPPNSF SSAGGQRTCD ICRQCKGVFR TRKECSSTSN AECDCTPGFH CLGAGCSMCE QDCKQGQELT KKGCKDCCFG TFNDQKRGIC RPWTNCSLDG KSVLVNGTKE RDVVCGPSPA DLSPGASSVT PPAPAREPGH SPQ
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
CD137 signaling maintains the survival of activated T cells and CD8+ memory T cells, promotes clonal expansion, and regulates cytokine release affecting monocyte survival. Soluble forms of CD137 may act as negative regulators of immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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