Thermo Fisher Scientific PP2A alpha Monoclonal Antibody (7A6)
PP2A alpha 단백질의 C-말단을 인식하는 mouse monoclonal antibody로, Human, Mouse, Rat, Yeast 시료에 반응합니다. Western blot, ICC/IF, IP 등 다양한 응용에 적합하며, 단백질 G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Yeast |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A6 |
| Immunogen | C-terminal peptide of human PP2A catalytic subunit (sequence: 302-RRTPDYFL-309) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539443 |
Product Specific Information
This antibody recognizes the C-terminal of PP2A, both alpha and beta isoforms, in human, mouse, rat, and S. cerevisiae samples.
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate diverse cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases are critical in this process and generally form a trimeric complex comprising a regulatory subunit, a variable subunit, and a catalytic subunit. Major protein phosphatase families include PP1, PP2A, PP2B (calcineurin), and PP2C. The PP2A family includes PP2A alpha and PP2A beta subfamily members. Another catalytic subunit, PPX (also known as PP4), is considered part of a novel PP family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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