Thermo Fisher Scientific Claudin 2 Polyclonal Antibody
Human과 Mouse 시료에서 Claudin 2 단백질을 검출하는 폴리클로날 항체. Western blot에 최적화되어 있으며, Rabbit IgG 기반으로 제작. KLH 결합 합성 펩타이드(190–220 aa)를 면역원으로 사용. 고순도 정제 및 안정적 저장 조건 제공.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Claudin 2 Polyclonal Antibody
Thermo Fisher Scientific Claudin 2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 190–220 amino acids from the C-terminal region of human Claudin 2 (CLDN2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2276436 |
Target Information
Tight junctions are specialized regions of cell-cell contact abundant in luminal epithelial sheets. In electron micrographs, they appear as belt-like sealing strands encircling each cell, forming a molecular gasket that prevents leakage of ions and molecules.
Beyond their barrier function, tight junctions also maintain epithelial polarity by blocking diffusion of membrane proteins between apical and basolateral surfaces.
Proteins such as ZO-1, ZO-2, ZO-3, cingulin, Rab-3b, and symplekin are associated with tight junctions, contributing to assembly, maintenance, and permeability regulation.
Claudin-1 and Claudin-2 are key structural components of tight junction strands, unlike occludin which plays an accessory role. Claudin-2 functions as a paracellular channel selective for cations (Na+) and is mainly expressed in liver and kidney, with minor expression in brain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(본 제품 관련 이미지가 있을 경우 이 섹션에 배치됩니다.)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.