Thermo Fisher Scientific H4K8ac Recombinant Rabbit Monoclonal Antibody (RM201), ChIP-Verified
Histone H4의 Lys8 아세틸화(K8ac)에 특이적으로 반응하는 재조합 토끼 단클론 항체로, ChIP 검증 완료. WB, ICC/IF, ELISA, ChIP, Luminex 등 다양한 응용에 적합. 높은 순도와 안정성으로 연구용에 최적화된 항체.
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Thermo Fisher Scientific H4K8ac Recombinant Rabbit Monoclonal Antibody (RM201), ChIP-Verified
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.5–2 µg/mL | - |
| ELISA | 0.2–1 µg/mL | - |
| ChIP assay (ChIP) | 1–5 µg | - |
| Luminex (LUM) | 0.05–1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM201 |
| Immunogen | An acetyl-peptide corresponding to Acetyl-Histone H4 (Lys8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| RRID | AB_2866513 |
Product Specific Information
This antibody reacts specifically with Histone H4 acetylated at Lysine 8 (K8ac) and shows no cross-reactivity with other acetylated lysines in Histone H4.
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Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction into higher-order structures.
This gene, part of the large histone gene cluster on chromosome 6, is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails and instead contain a palindromic termination element.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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