Thermo Fisher Scientific H4K12ac Recombinant Rabbit Monoclonal Antibody (RM202), ChIP-Verified
Histone H4 Lys12 acetyl화(K12ac)에 특이적으로 반응하는 재조합 토끼 단일클론 항체입니다. ChIP 검증 완료, WB·ICC·ELISA·Luminex 등 다양한 응용 가능. Human 시료 반응성, Protein A 정제, 고농도(1 mg/mL) 액상 형태로 제공.
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Thermo Fisher Scientific H4K12ac Recombinant Rabbit Monoclonal Antibody (RM202), ChIP-Verified
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.5–2 µg/mL | - |
| ELISA | 0.5–1 µg/mL | - |
| ChIP assay (ChIP) | 1–5 µg | - |
| Luminex (LUM) | 0.5–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM202 |
| Immunogen | Acetyl-peptide corresponding to Acetyl-Histone H4 (Lys12) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| RRID | AB_2815526 |
Product Specific Information
This antibody specifically reacts with Histone H4 acetylated at Lysine 12 (K12ac) and shows no cross-reactivity with other acetylated lysines in Histone H4.
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Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer, around which ~146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and facilitates chromatin compaction into higher-order structures.
This gene, located on chromosome 6, is intronless and encodes a member of the histone H4 family. Its transcripts lack polyA tails and instead contain a palindromic termination element.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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