Thermo Fisher Scientific Tyrosinase Monoclonal Antibody (T311)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

View 5 publications 5 publications

Immunohistochemistry (IHC)

Assay-dependent

View 4 publications 4 publications

Flow Cytometry (Flow)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Rat

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

T311

Immunogen

Recombinant tyrosinase protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533214

Target Information

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3` half of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.