Thermo Fisher Scientific NY-ESO-1 Monoclonal Antibody (E978)
Human NY-ESO-1 단백질을 특이적으로 인식하는 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며 연구용으로 사용. 장기 보관 시 -20°C에서 안정적 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 7 publications |
| Immunohistochemistry (IHC) | – | View 11 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL | View 8 publications |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Flow Cytometry (Flow) | – | View 7 publications |
| ELISA | – | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 9 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E978 |
| Immunogen | Human NY-ESO-1 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533215 |
Product Specific Information
This antibody reacts specifically with the 23 kDa NY-ESO-1 protein. Reactivity was confirmed with human SKMEL-37 melanoma cells during development.
Target Information
NY-ESO-1 is a member of the CT (cancer/testis) family and a tumor-specific shared antigen with distinctive immunogenicity. It plays a key role in T cell-mediated antitumor immunity, recognized by CD8+ T cells. Both cytotoxic T lymphocytes and antibodies can react with this antigen. NY-ESO-1 is detected in normal testis and various human tumor types, with testis reactivity restricted to germ cells, particularly spermatogonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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