Thermo Fisher Scientific MAGE1 Monoclonal Antibody (6C1)
인간 MAGE1 단백질을 인식하는 마우스 단클론 항체로 다양한 암 연구에 활용 가능. Western blot, IHC, ELISA 등에서 사용. 단백질 A로 정제된 액상형 항체이며 PBS buffer에 0.1% sodium azide 포함. 암 면역치료 표적 연구용으로 적합.
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Thermo Fisher Scientific MAGE1 Monoclonal Antibody (6C1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Dog, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C1 |
| Immunogen | Full-length recombinant human MAGE-A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533216 |
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, cytolytic CD8+ T lymphocyte clones (CTLs). An important group of these antigens is coded by the MAGE family of genes. MAGE-1 is expressed in a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) but not in normal tissues. Therefore, the encoded antigen may serve as a marker for early detection and as a target for cancer immunotherapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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