Thermo Fisher Scientific LYRIC/AEG1 Recombinant Rabbit Monoclonal Antibody (BLR258L)
LYRIC/AEG1 단백질을 인식하는 Rabbit Monoclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ICC/IF, Flow Cytometry, IP 등 다양한 응용에 사용 가능하며, 1 mg/mL 농도의 액상 정제 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR258L |
| Immunogen | Peptide representing a region between residue 450 and 500 of Human protein LYRIC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Metadherin (Metastasis adhesion protein), also known as MTDH or LYRIC (LYsine-RIch CEACAM1 co-isolated), is a protein associated with tight junctions in polarized epithelial cells. It localizes with tight junction proteins such as ZO-1 and occludin, not as a structural component but during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissues and xenografts, with much lower expression in normal breast tissue. It binds to lung vasculature through a C-terminal extracellular domain segment, and blocking this domain has been shown to inhibit breast cancer metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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