Thermo Fisher Scientific CTLA4 Recombinant Rabbit Monoclonal Antibody (BLR257L)
CTLA4 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간 시료에 반응합니다. 고순도 액상 형태로 제공되며, 4°C에서 안정적으로 보관 가능합니다.
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Thermo Fisher Scientific CTLA4 Recombinant Rabbit Monoclonal Antibody (BLR257L)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR257L |
| Immunogen | Peptide representing a region between residue 173 and the C-terminus (residue 223) of Human Cytotoxic T-lymphocyte protein 4 (CTLA-4, CD152; UniProt ID: P16410-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Product is tested in Multiplex Immunofluorescence (mIF).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor primarily expressed on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may play a key role in their suppressive function.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(A700-257_CTLA-4_CD152_P16410-1_Rabbit.svg 및 A700-257_CTLA-4_CD152_P16410-1_Rabbit_PDP.jpeg)
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