Thermo Fisher Scientific SERPINC1 Polyclonal Antibody
Human SERPINC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SERPINC1. Recombinant protein control fragment (Product # RP-99383) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790018 |
Product Specific Information
Immunogen sequence:
PSEAINELTV LVLVNTIYFK GLWKSKFSPE NTRKELFYKA DGESCSASMM YQEGKFRYRR VAEGTQVLEL PFKGDDITMV LILPKPEKSL AKVEKELTPE VLQEWLDELE EMMLVVHMPR FRIEDGFSLK EQLQDMGLV
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily.
This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade.
It includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus.
The inhibitory activity is enhanced by the presence of heparin.
More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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