Thermo Fisher Scientific PHGDH Polyclonal Antibody
Thermo Fisher Scientific의 PHGDH Polyclonal Antibody는 인간 PHGDH 단백질을 인식하는 토끼 다클론 항체입니다. Western blot, IHC, ICC/IF에 적합하며 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PHGDH. Recombinant protein control fragment (Product # RP-91731) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790019 |
Product Specific Information
Immunogen sequence:
KVLISDSLDP CCRKILQDGG LQVVEKQNLS KEELIAELQD CEGLIVRSAT KVTADVINAA EKLQVVGRAG TGVDNVDLEA ATRKGILVMN T
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is essential for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene are associated with congenital microcephaly, psychomotor retardation, and other symptoms. Multiple alternatively spliced transcript variants have been identified, though most full-length forms remain uncharacterized.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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